2 products were found matching "911715-90-7"!

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Item number: Cay28419-1

AZD 8797 is a chemokine (C-X3-C motif) receptor 1 (CX3CR1) antagonist (Ki = 3.9 nM). It is selective for CX3CR1 over CX3CR2 (Ki = 2,800 nM). AZD 8797 (0.1-10 µM) inhibits [35S]GTPgammaS accumulation induced by chemokine (C-X3-C) ligand 1 (CX3CL1) in CHO cell membranes expressing human CX3CR1. It inhibits adhesion of...

Keywords:	(2R)-2-[[2-amino-5-[[(1S)-1-phenylethyl]thio]thiazolo[4,5-d]pyrimidin-7-yl]amino]-4-methyl-1-pentanol
Application:	CX3CR1 antagonist
CAS	911715-90-7
MW:	403.6 D

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AZD8797

Item number: TGM-T14384-100mg

Description: AZD8797 (KAND567) is an orally available, selective and potent human CX3CR1-converting antagonist with inhibitory effects on CX3CR1 and CXCR2, and potentially protects against SARS-CoV-2-induced neuronal damage, preventing worsening of nociceptive sensitization and microglial activation in a migraine...

Keywords:	KAND567, KAN-0440567
Application:	CX3CR1 antagonist
CAS	911715-90-7
MW:	403.56 D

From 76.00€ *

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