2 products were found matching "911417-87-3"!
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KD 025
Item number: Cay17055-10
KD 025 is an inhibitor of Rho-associated kinase 2 (ROCK2, IC50 = 0.105 µM). It is selective for ROCK2 over ROCK1 (IC50 = 24 µM). KD 025 (10 µM) decreases the expression of connective tissue growth factor (CTGF) and induces remodeling of the actin cytoskeleton in isolated human ileal fibrotic smooth muscle cells. It...
| Keywords: | SLx-2119, 2-[3-[4-(1H-indazol-5-ylamino)-2-quinazolinyl]phenoxy]-N-(1-methylethyl)-acetamide |
| Application: | ROCK2 inhibitor |
| CAS | 911417-87-3 |
| MW: | 452.5 D |
From 88.00€
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Belumosudil
Item number: TGM-T6867-2mg
Description: Belumosudil (Rezurock) is an orally available, and specific ROCK2 inhibitor (IC50/Ki: 60/41 nM). Target: ROCK. Smiles: CC(C)NC(=O)COc1cccc(c1)-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1. References: Lee JH, et al. Ann Clin Transl Neurol. 2014, 1(1), 2-14.
| Keywords: | KD025, Rezurock, ROCK inhibitor, SLx-2119 |
| Application: | Targets Rho-associated protein kinase 2 [EC:2.7.11.39] (ROCK2) |
| CAS | 911417-87-3 |
| MW: | 452.51 D |
From 39.00€
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