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Pitolisant hydrochloride
Pitolisant hydrochloride

Item number: TGM-T7176-100mg

Description: Pitolisant hydrochloride (Ciproxidine) is a potent and selective inverse agonist of the histamine H3 receptor(Ki : 0.16 nM). Target: Histamine Receptor. Smiles: Cl.Clc1ccc(CCCOCCCN2CCCCC2)cc1. References: Kotanska Magdalena, Kuder K J , Szczepanska Katarzyna, et al. The histamine H3 receptor inverse...
Keywords: Ciproxidine, BF 2649
Application: Targets histamine receptor H3 (HRH3)
CAS 903576-44-3
MW: 332.31 D
From 43.00€ *
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Pitolisant
Pitolisant

Item number: Cay19307-1

Pitolisant is a nonimidazole histamine H3 receptor antagonist (Ki = 0.16 nM) and inverse agonist (EC50 = 1.5 nM). It increases the levels of tele-methylhistamine in mouse brain, indicating histaminergic neuron activity, with an ED50 value of 1.6 mg/kg. Pitolisant also increases dopamine and acetylcholine levels in...
Keywords: BF 2649, 1-[3-[3-(4-chlorophenyl)propoxy]propyl]-piperidine, monohydrochloride
Application: Histamine H3 receptor antagonist / inverse agonist
CAS 903576-44-3
MW: 332.3 D
From 52.00€ *
Review