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Item number: Cay18604-1

The kinase Akt (also known as protein kinase B or PKB) modulates cell proliferation, metabolism, and survival, as well as angiogenesis. Akt inhibitor XI is a cell-permeable, copper-containing 3-formylchromone derivative that inhibits Akt in an array of cancer cells (IC50s = 10-34 µM). It also causes NF-kappaB...

Keywords:	FPA-124, (SP-4-3)-dichloro[(2Z)-2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazinecarbothioamide-kappaN2,kappaS]-copper
Application:	PKB inhibitor
CAS	902779-59-3
MW:	381.7 D

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