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Trifarotene
Item number: Cay45281-10
A RARgamma agonist, selective for RARgamma over RARalpha and RARbeta in reporter assays using HeLa cells expressing chimeric RARgamma, RARalpha, or RARbeta receptors (EC50s = 7.7, 498, and 125 nM, respectively) and is inactive at the retinoid X receptor (RXR), reduces TPA-induced ear edema in a mouse model of...
| Keywords: | CD5789, 3''-(1,1-dimethylethyl)-4'-(2-hydroxyethoxy)-4''-(1-pyrrolidinyl)-[1,1':3',1''-terphenyl]-4-carboxylic acid |
| Application: | RARgamma agonist |
| CAS | 895542-09-3 |
| MW: | 459.59 D |
From 107.00€
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trifarotene
Item number: TGM-T7586-100mg
Description: Trifarotene (CD5789) is a potent and selective RARgamma agonist, exhibiting 65-fold and 16-fold selectivity for RARgamma (EC50=7.7 nM) over RARalpha (EC50=500 nM) and RARbeta (EC50=125 nM). Target: Autophagy, Retinoid Receptor. Smiles: CC(C)(C)c1cc(ccc1N1CCCC1)-c1cc(ccc1OCCO)-c1ccc(cc1)C(O)=O....
| Keywords: | CD5789 |
| Application: | Targets retinoic acid receptor gamma (RARG, NR1B3) |
| CAS | 895542-09-3 |
| MW: | 459.58 D |
From 34.00€
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