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DMOG
Item number: Cay71210-100
The pro-angiogenic factor HIF-1alpha is targeted for destruction in normoxic environments by the hydroxylation of a specific proline residue, P564, by the oxygen-sensing enzyme HIF-1alpha prolyl hydroxylase (HIF-PH). DMOG is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1alpha...
| Keywords: | Dimethyloxallyl Glycine, N-(methoxyoxoacetyl)-glycine, methyl ester |
| Application: | HIF-PH inhibitor |
| CAS | 89464-63-1 |
| MW: | 175.1 D |
From 27.00€
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DMOG
Item number: TGM-T1939-100mg
Description: DMOG (Dimethyloxalylglycine), an antagonist of the alpha-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase. Target: HIF/HIF Prolyl-Hydroxylase, HIF, Autophagy. Smiles: COC(=O)CNC(=O)C(=O)OC. References: Singh A, et al. Hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitors...
| Keywords: | Dimethyloxallyl Glycine, Dimethyloxalylglycine, Dimethyloxaloylglycine |
| Application: | HIF-PH inhibitor |
| CAS | 89464-63-1 |
| MW: | 175.14 D |
From 46.00€
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