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VU 0240551
Item number: TGM-TQ0139-100mg
Description: VU 0240551 is a selective antagonist of neuronal K-Cl cotransporter KCC2 inhibitor with an IC50 of 560 nM. VU 0240551 inhibits L-type calcium channels and hERG. Target: Calcium Channel, HER, Potassium Channel. Smiles: S(CC(NC=1SC=C(C)N1)=O)C2=CC=C(N=N2)C3=CC=CC=C3. References: Delpire E, et al....
| Keywords: | N-(4-Methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide, VU0240551-2-D4 |
| Application: | KCC2 inhibitor |
| CAS | 893990-34-6 |
| MW: | 342.44 D |
From 31.00€
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VU0240551
Item number: Cay29790-10
VU0240551 is a K+/Cl- cotransporter 2 (KCC2) inhibitor (IC50 = 568 nM). It selectively inhibits KCC2 over Na+/K+/Cl- cotransporter 1 (NKCC1, IC50 = >50 µM) but does inhibit the activity of adenosine A1 and A3 receptors, as well as inhibits activity of L-type calcium channels at the benzothiazepine site and human...
| Keywords: | N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]-acetamide |
| Application: | KCC2 inhibitor |
| CAS | 893990-34-6 |
| MW: | 342.4 D |
From 107.00€
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