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Item number: TGM-T8546-100mg

Description: BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 µM and 1.1 µM in mouse and human T cells, respectively). Target: JAK, STAT. Smiles: Oc1c2CCCCc2nn1-c1nc2ccccc2s1. References: Yan Zhou, et al. Tolerogenic...

CAS	892686-59-8
MW:	271.34 D

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BD 750

Item number: Cay37574-10

BD 750 is an immunosuppressant. It inhibits the proliferation of primary human and mouse T cells (IC50s = 1.1 and 1.5 µM, respectively) without inducing cytotoxicity when used at concentrations ranging from 3.13 to 50 µM. BD 750 induces cell cycle arrest at the G0/G1 phases in CD3 and CD28 antibody-activated primary...

Keywords:	2-(2-benzothiazolyl)-4,5,6,7-tetrahydro-2H-indazol-3-ol
Application:	Immunosuppressant
CAS	892686-59-8
MW:	271.3 D

From 40.00€ *

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