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S3QEL-2
S3QEL-2

Item number: Cay18556-5

S3QEL-2 is a cell-permeable, selective suppressor of electron leak from mitochondrial respiratory complex III, inhibiting site IIIQo superoxide production (IC50 = 1.7 µM) without altering normal bioenergetics function. It reduces production of H2O2 during oxidation of glutamate plus malate to 25% of the control...
Keywords: 1-(3,4-dimethylphenyl)-N,N-dipropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Application: Mitochondrial complex III superoxide production suppressor
CAS 890888-12-7
MW: 323.4 D
From 56.00€ *
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S3QEL-2
S3QEL-2

Item number: TGM-T26172-1mL

Description: S3QEL-2 is a retrograde signaling modulator. It acts by strongly mitigating the oxidative stress-induced apoptosis that limits the yield of functional ß-cells from intact islets. Target: Others. Smiles: CCCN(CCC)c1ncnc2n(ncc12)-c1ccc(C)c(C)c1. References: Orr AL, Vargas L, Turk CN, Baaten JE, Matzen JT,...
Keywords: S3QEL 2, S3QEL2
CAS 890888-12-7
MW: 323.44 D
44.00€ *
Review