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Verdiperstat
Item number: TGM-T5463-100mg
Description: Verdiperstat (AZD 3241) is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and can be used in the research of neurodegenerative brain disorders. Target: Glutathione Peroxidase. Smiles: CC(C)OCCn1c2cc[nH]c2c(=O)[nH]c1=S. References: Johnström P, et al....
| Keywords: | AZD3241, AZD 3241 |
| Application: | Targets myeloperoxidase [EC:1.11.2.2] (MPO) |
| CAS | 890655-80-8 |
| MW: | 253.32 D |
From 33.00€
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Verdiperstat
Item number: Cay37333-10
Verdiperstat is an irreversible inhibitor of myeloperoxidase (MPO, IC50 = 630 nM), a redox enzyme involved in oxidative stress. It is selective for MPO over a panel of 130 enzymes, transporters, and ion channels (IC50s = >50 µM for all). Oral administration of verdiperstat (180 µmol/kg) reduces MPO expression,...
| Keywords: | AZD 3241, BHV 3421, 1,2,3,5-tetrahydro-1-[2-(1-methylethoxy)ethyl]-2-thioxo-4H-pyrrolo[3,2-d]pyrimidin-4-one |
| Application: | Irreversible MPO inhibitor |
| CAS | 890655-80-8 |
| MW: | 253.3 D |
From 57.00€
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