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Supinoxin
Supinoxin

Item number: Cay36573-1

Supinoxin is an inhibitor of Y593-phosphorylated DEAD-box helicase 5 (DDX5). It binds to Y593-phosphorylated DDX5 (Kd = ~19 nM), but does not interact with unphosphorylated DDX5, and selectively inhibits beta-catenin-dependent ATPase activity over RNA-dependent ATPase activity at 0.2 µM. Supinoxin induces apoptosis...
Keywords: RX-5902, 4-(3,5-dimethoxyphenyl)-N-(7-fluoro-3-methoxy-2-quinoxalinyl)-1-piperazinecarboxamide
Application: Tyr593-phosphorylated DDX5 inhibitor
CAS 888478-45-3
MW: 441.5 D
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