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trans-AUCB
Item number: TGM-T17158-5mg
Description: trans-AUCB (t-AUCB) is an effective and selective soluble epoxide hydrolase inhibitor, with IC50 values of 1.3 nM for hsEH, 8 nM for mouse sEH, and 8 nM for rat sEH. Target: Epoxide Hydrolase. Smiles: OC(=O)c1ccc(OC2CCC(CC2)NC(=O)NC23CC4CC(CC(C4)C2)C3)cc1. References: Li J, et al. t-AUCB, an improved...
| Keywords: | t-AUCB |
| Application: | Soluble epoxide hydrolase inhibitor |
| CAS | 885012-33-9 |
| MW: | 412.52 D |
From 45.00€
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trans-AUCB
Item number: Cay16568-1
Soluble epoxide hydrolase (sEH) converts epoxides to their corresponding diols. Inhibitors of sEH have anti-inflammatory, anti-hypertensive, neuroprotective, and cardioprotective effects. trans-AUCB is a very potent inhibitor of sEH (IC50 = 0.5 nM). It displays high oral bioavailability for doses ranging from 0.01...
| Keywords: | 4-[[trans-4-[[(tricyclo[3.3.1.13,7]dec-1-ylamino)carbonyl]amino]cyclohexyl]oxy]-benzoic acid |
| Application: | Soluble epoxide hydrolase inhibitor |
| CAS | 885012-33-9 |
| MW: | 412.5 D |
From 44.00€
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