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Item number: Cay34259-5

Anle138b is an inhibitor of protein aggregation. It inhibits alpha-synuclein oligomer formation and PrPSc prion propagation by 77 and 84%, respectively, when used at a concentration of 10 µM. Anle138b (1 mg/animal) inhibits brain accumulation of PrPSc in, and increases survival of, prion-infected mice. It reduces...

Keywords:	3-(1,3-benzodioxol-5-yl)-5-(3-bromophenyl)-1H-pyrazole
Application:	Protein aggregation inhibitor
CAS	882697-00-9
MW:	343.2 D

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Anle138b

Item number: TGM-T5447-100mg

Description: Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease. Target: Beta Amyloid. Smiles: Brc1cccc(c1)-c1cc(n[nH]1)-c1ccc2OCOc2c1. References: Wagner J, et al. Anle138b: a novel oligomer modulator for disease-modifying therapy...

Application:	Protein aggregation inhibitor
CAS	882697-00-9
MW:	343.17 D

From 38.00€ *

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