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P005091
Item number: TGM-T6925-100mg
Description: P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 µM. Target: DUB. Smiles: CC(=O)c1cc(c(Sc2cccc(Cl)c2Cl)s1)[N+]([O-])=O. References: Chauhan D, et al. Cancer Cell, 2012, 22(3), 345-358.
| Keywords: | P5091 |
| Application: | USP7 / USP47 inhibitor |
| CAS | 882257-11-6 |
| MW: | 348.22 D |
From 40.00€
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P005091
Item number: Cay15224-5
Ubiquitin-specific proteases (USP/UBP) remove ubiquitin from proteins, sparing them from degradation by the proteasome. USP7 is a cysteine protease associated with prostate cancer that selectively deubiquitylates HDM2, the ubiquitin E3 ligase for the tumor suppressor p53. P005091 is a trisubstituted thiophene that...
| Keywords: | P5091, 1-[5-[(2,3-dichlorophenyl)thio]-4-nitro-2-thienyl]-ethanone |
| Application: | USP7 / USP47 inhibitor |
| CAS | 882257-11-6 |
| MW: | 348.2 D |
From 91.00€
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