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DuP-697
Item number: Cay70645-5
DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2. When tested on isolated recombinant enzymes, DuP-697 is at least 50 times more potent in the inhibition of COX-2...
| Keywords: | 5-bromo-2-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)-thiophene |
| Application: | COX-2 inhibitor |
| CAS | 88149-94-4 |
| MW: | 411.3 D |
From 169.00€
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DuP-697
Item number: TGM-T15181-100mg
Description: DuP-697 is an irreversible and specific inhibitor of COX-2 with IC50 values of 10 nM and 800 nM for human COX-2 and COX-1. DuP-697 shows antiproliferative activity with an IC50 of 42.8 nM. DuP-697 exhibits antiangiogenic, anti-inflammatory, antipyretic and apoptotic effects. Target: COX. Smiles:...
| Application: | COX-2 inhibitor |
| CAS | 88149-94-4 |
| MW: | 411.31 D |
From 46.00€
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