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Phthalazinone pyrazole
Item number: Cay10735-1
Three Aurora kinases, A-C, are involved in phosphorylation events that are critical for the completion of mitosis. Aurora A, involved in centrosomal assembly and acentrosomal spindle assembly, is overexpressed in many tumors. Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase (IC50 = 31 nM). It does not...
| Keywords: | 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2H-phenyl-1-phthalazinone |
| CAS | 880487-62-7 |
| MW: | 317.4 D |
From 102.00€
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Phthalazinone pyrazole
Item number: Cay10735-10
Three Aurora kinases, A-C, are involved in phosphorylation events that are critical for the completion of mitosis. Aurora A, involved in centrosomal assembly and acentrosomal spindle assembly, is overexpressed in many tumors. Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase (IC50 = 31 nM). It does not...
| Keywords: | 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2H-phenyl-1-phthalazinone |
| CAS | 880487-62-7 |
| MW: | 317.4 D |
From 102.00€
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Phthalazinone pyrazole
Item number: Cay10735-5
Three Aurora kinases, A-C, are involved in phosphorylation events that are critical for the completion of mitosis. Aurora A, involved in centrosomal assembly and acentrosomal spindle assembly, is overexpressed in many tumors. Phthalazinone pyrazole is a potent inhibitor of Aurora A kinase (IC50 = 31 nM). It does not...
| Keywords: | 4-[(5-methyl-1H-pyrazol-3-yl)amino]-2H-phenyl-1-phthalazinone |
| CAS | 880487-62-7 |
| MW: | 317.4 D |
From 102.00€
*
Phthalazinone pyrazole
Item number: TGM-T21981-100mg
Description: Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity. Target: Apoptosis, Aurora Kinase. Smiles: Cc1cc(Nc2nn(-c3ccccc3)c(=O)c3ccccc23)n[nH]1
| CAS | 880487-62-7 |
| MW: | 317.34 D |
From 55.00€
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Phthalazinone pyrazole
Item number: TGM-T21981-10mg
Description: Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity. Target: Apoptosis, Aurora Kinase. Smiles: Cc1cc(Nc2nn(-c3ccccc3)c(=O)c3ccccc23)n[nH]1
| CAS | 880487-62-7 |
| MW: | 317.34 D |
From 55.00€
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Phthalazinone pyrazole
Item number: TGM-T21981-1mg
Description: Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity. Target: Apoptosis, Aurora Kinase. Smiles: Cc1cc(Nc2nn(-c3ccccc3)c(=O)c3ccccc23)n[nH]1
| CAS | 880487-62-7 |
| MW: | 317.34 D |
From 55.00€
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Phthalazinone pyrazole
Item number: TGM-T21981-25mg
Description: Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity. Target: Apoptosis, Aurora Kinase. Smiles: Cc1cc(Nc2nn(-c3ccccc3)c(=O)c3ccccc23)n[nH]1
| CAS | 880487-62-7 |
| MW: | 317.34 D |
From 55.00€
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Phthalazinone pyrazole
Item number: TGM-T21981-50mg
Description: Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity. Target: Apoptosis, Aurora Kinase. Smiles: Cc1cc(Nc2nn(-c3ccccc3)c(=O)c3ccccc23)n[nH]1
| CAS | 880487-62-7 |
| MW: | 317.34 D |
From 55.00€
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Phthalazinone pyrazole
Item number: TGM-T21981-5mg
Description: Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity. Target: Apoptosis, Aurora Kinase. Smiles: Cc1cc(Nc2nn(-c3ccccc3)c(=O)c3ccccc23)n[nH]1
| CAS | 880487-62-7 |
| MW: | 317.34 D |
From 55.00€
*