2 products were found matching "878437-15-1"!
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PA-8
Item number: Cay42131-10
A PAC1 receptor antagonist, selectively inhibits PACAP-induced CREB phosphorylation in CHO cells expressing the PAC1 receptor over CHO cells expressing VPAC1 or VPAC2 at 10 nM, inhibits PACAP-induced cAMP accumulation in CHO cells expressing the PAC1 receptor (IC50 = 2 nM), intrathecal administration reduces...
| Keywords: | 2-amino-5,8-dihydro-5-[3-methoxy-4-(2-propen-1-yloxy)phenyl]-pyrido[2,3-d]pyrimidine-4,7(3H,6H)-dione |
| Application: | PAC1 receptor antagonist |
| CAS | 878437-15-1 |
| MW: | 342.4 D |
From 58.00€
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PA-8
Item number: TGM-T41005-100mg
Description: PA-8 is a small molecule receptor antagonist for PACAP Type I (PAC1) that is selective, effective, and orally active. PA-8 inhibits PacAP-induced CREB phosphorylation at PAC1- receptors, but does not inhibit VPAC1- or vpac2 receptors. PA-8 also inhibited PacAP-induced elevation of cAMP levels in vitro...
| CAS | 878437-15-1 |
| MW: | 342.35 D |
From 38.00€
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