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F-Amidine TFA
Item number: TGM-T84479-10mg
Description: F-amidine is a selective inhibitor of protein arginine deiminases (PADs), specifically targeting PAD1 and PAD4 with in vitro IC50 values of 29.5, 350, and 21.6 µM for PAD1, PAD3, and PAD4, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine...
| Application: | Peptidyl arginine deiminase (PAD) inhibitor |
| CAS | 877617-46-4 |
| MW: | 408.4 D |
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F-Amidine (trifluoroacetate salt)
Item number: Cay10610-250
F-amidine is an inhibitor of protein arginine deiminases (PADs) that is selective for PAD1 and PAD4 (IC50s = 29.5, 350, and 21.6 µM for PAD1, PAD3, and PAD4 in vitro, respectively). It irreversibly inactivates all four PAD subtypes (kinact/KI = 2,800, 380, 170, and 3,000 M-1min-1 by covalently modifying an active...
| Keywords: | N-[(1S)-1-(aminocarbonyl)-4-[(2-fluoro-1-iminoethyl)amino]butyl]-benzamide, 2,2,2-trifluoroacetate |
| Application: | Peptidyl arginine deiminase (PAD) inhibitor |
| CAS | 877617-46-4 |
| MW: | 408.4 D |
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