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Item number: Cay40436-10

Tandospirone is a partial agonist of the serotonin (5-HT) receptor subtype 5-HT1A. It selectively binds to 5-HT1A receptors (Ki = 0.027 µM) over 5-HT2, 5-HT1B, 5-HT1C, and 5-HT1D receptors (Kis = 1.3, >100, 2.6, and >100 µM, respectively), as well as alpha1-adrenergic receptors (alpha1-ARs), alpha2-ARs, beta-ARs,...

Keywords:	SM-3997, (3aR,4S,7R,7aS)-rel-hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione
Application:	5-HT1A partial agonist
CAS	87760-53-0
MW:	383.5 D

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Tandospirone

Item number: TGM-TQ0315-1mL

Description: Tandospirone (SM-3997) is a selective and potent 5-HT1A receptor partial agonist with anxiolytic and antidepressant activity that potentiates the anticardiac fibrotic effect of valsartan in spontaneously hypertensive rats, and can be used in the study of central nervous system disorders. Target: 5-HT...

Keywords:	SM3997 , SM-3997
Application:	Targets 5-hydroxytryptamine receptor 1 (HTR1)
CAS	87760-53-0
MW:	383.49 D

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