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Item number: Cay29774-1

NS 8593 is an inhibitory gating modifier of small-conductance calcium-activated potassium (KCa2/SK) channels (Kds = 0.42, 0.6, and 0.73 µM for KCa2.1/SK1, KCa2.2/SK2, and KCa2.3/SK3, respectively, in the presence of calcium) that decreases the calcium sensitivity of SK channels. It is selective for KCa2/SK channels...

Keywords:	N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-1H-benzimidazol-2-amine, monohydrochloride
Application:	Selective KCa2 (SK) channel negative modulator
CAS	875755-24-1
MW:	299.8 D

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NS8593 hydrochloride

Item number: TGM-T12256-1mg

Description: NS8593 hydrochloride (NS8593 HCl) is a potent and selective inhibitor of small conductance Ca2+-activated K+ channels (SK channels) . Target: Potassium Channel. Smiles: Cl.C1C[C@@H](Nc2nc3ccccc3[nH]2)c2ccccc2C1. References: Sørensen US, et al. Synthesis and structure-activity relationship studies of...

Keywords:	NS8593 HCl
Application:	Selective KCa2 (SK) channel negative modulator
CAS	875755-24-1
MW:	299.8 D

From 37.00€ *

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