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MGCD-265
MGCD-265

Item number: Cay20097-1

MGCD-265 is an inhibitor of c-Met and VEGFR2 (IC50s = 0.029 and 0.01 µM, respectively). It is selective for c-Met and VEGFR2 over Chk1, EGFR, GSK3beta, IGF-1R, IKKbeta, JAK2, and JNK1 at 0.1 µM but also inhibits VEGFR1, VEGFR3, Ron, Tie2, FLT3, c-Kit, Abl, and TrkA with percent inhibition values ranging from 80 to...
Keywords: N-[[[3-fluoro-4-[[2-(1-methyl-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yl]oxy]phenyl]amino]thioxomethyl]-benzeneacetamide
Application: Tyrosine kinase inhibitor
CAS 875337-44-3
MW: 517.6 D
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