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Item number: Cay17810-10

Inhibitor of apoptosis proteins (IAPs), which block various signaling pathways leading to apoptotic cell death, are commonly over-expressed in cancer cells. GDC-0152 is a potent inhibitor of specific IAPs that binds baculoviral IAP repeat (BIR) domains (Kis = 28, 14, 17, and 43 nM for XIAP BIR3, NL-IAP BIR, BIRC2...

Keywords:	N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-L-prolinamide
Application:	Caspase activator
CAS	873652-48-3
MW:	498.6 D

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GDC-0152 Free Base

Item number: LKT-G124086.1

GDC-0152 is an X-linked inhibitor of apoptosis protein (XIAP). GDC-0152 induces apoptosis in several cell lines including HL-60, NB4, osteosarcoma, glioblastomas among others.

Keywords:	GDC0152, GDC 0152, N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-L-prolinamide
Application:	Apoptosis inducer
CAS	873652-48-3
MW:	498.65 D

From 77.00€ *

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