Description: Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Target: RAAS. Smiles: C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1[C@H]2CCC[C@H]2C[C@H]1C(O)=O. References: Safari F , Bayat G , Shekarforoush S , et al. Expressional profile of cardiac uncoupling protein-2...

Ramiprilat is the active metabolite of ramipril (Cay-15558) and functions as an angiotensin-converting enzyme inhibitor (pKi = 9.08 in human heart) to suppress the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, thereby preventing vasoconstriction. Furthermore, ramiprilat is reported...