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INCB 13739
Item number: Cay40223-10
INCB 13739 is an inhibitor of 11beta-hydroxysteroid dehydrogenase 1 (11beta-HSD1, IC50 = 3.2 nM). It is greater than 1,000-fold selective for 11beta-HSD1 over 11beta-HSD2, the mineralocorticoid receptor, and the glucocorticoid receptor at 5 µM. INCB 13739 inhibits 11beta-HSD1 activity in peripheral blood mononuclear...
| Keywords: | (3S)-1-[(3-chloro-2-methylphenyl)sulfonyl]-N-cyclohexyl-3-piperidinecarboxamide |
| Application: | 11beta-HSD1 inhibitor |
| CAS | 872506-67-7 |
| MW: | 398.9 D |
From 112.00€
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11beta-HSD1-IN-12
Item number: TGM-T72814-100mg
Description: 11beta-HSD1-IN-12 is an 11beta-HSD1 inhibitor.11beta-HSD1-IN-12 is implicated in the conversion of glucocorticoids in vivo and can be used to study metabolic syndrome and obesity. Target: Dehydrogenase. Smiles: Cc1c(Cl)cccc1S(=O)(=O)N1CCC[C@@H](C1)C(=O)NC1CCCCC1. References: Wenqing Yao, et al....
| Application: | 11beta-HSD1 inhibitor |
| CAS | 872506-67-7 |
| MW: | 398.95 D |
From 77.00€
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