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TAK-285
Item number: SYN-1153-M001
Soluble in DMSO or ethanol. TAK-285 is a novel investigational dual HER2/EGFR inhibitor with IC(50) values of 17 and 23nM, respectively. Target: EGFR - HER2 , Kinase Group: RTK , Substrate: Tyrosine
| Keywords: | TAK285 |
| Application: | EGFR / HER2 inhibitor |
| CAS | 871026-44-7 |
| MW: | 548 D |
From 254.00€
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TAK-285
Item number: Cay29157-1
TAK-285 is a dual inhibitor of EGFR and HER2 (IC50s = 23 and 17 nM, respectively). It is selective for EGFR and HER2 over a panel of 36 kinases (IC50s = 250->10,000 nM). TAK-285 inhibits the proliferation of BT474 breast cancer cells (GI50 = 17 nM) as well as induces tumor regression in a 4-1st gastric...
| Keywords: | N-[2-[4-[[3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl]amino]-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-3-hydroxy-3-methyl-b... |
| Application: | EGFR / HER2 dual inhibitor |
| CAS | 871026-44-7 |
| MW: | 548 D |
From 44.00€
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TAK-285
Item number: TGM-T6039-100mg
Description: TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1. Target: MEK, EGFR, Aurora Kinase, HER. Smiles:...
| Keywords: | TAK285 , TAK 285 |
| Application: | EGFR / HER2 dual inhibitor |
| CAS | 871026-44-7 |
| MW: | 547.96 D |
From 31.00€
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