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Item number: Cay33346-1

Evocalcet is an agonist of the calcium-sensing receptor (CaSR). It induces intracellular calcium release in HEK293 cells expressing human CaSR (EC50 = 92.7 nM). Evocalcet reduces serum levels of parathyroid hormone (PTH) and calcium when administered at doses of 0.3 and 0.1 mg/kg, respectively, in non-nephrectomized...

Keywords:	KHK7580, MT-4580, 4-[(3S)-3-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-1-pyrrolidinyl]-benzeneacetic acid
Application:	CaSR agonist
CAS	870964-67-3
MW:	374.5 D

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