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Item number: TGM-T15261-100mg

Description: Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR). Target: CaSR. Smiles: C[C@@H](N[C@H]1CCN(C1)c1ccc(CC(O)=O)cc1)c1cccc2ccccc12. References: Tanimura, Shinji, et al. Pharmaceutical composition containing aryl alkyl amine compound. WO 2017061621 A1.

Keywords:	KHK7580
Application:	Targets calcium-sensing receptor (CASR)
CAS	870964-67-3
MW:	374.48 D

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Evocalcet

Item number: Cay33346-1

Evocalcet is an agonist of the calcium-sensing receptor (CaSR). It induces intracellular calcium release in HEK293 cells expressing human CaSR (EC50 = 92.7 nM). Evocalcet reduces serum levels of parathyroid hormone (PTH) and calcium when administered at doses of 0.3 and 0.1 mg/kg, respectively, in non-nephrectomized...

Keywords:	KHK7580, MT-4580, 4-[(3S)-3-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-1-pyrrolidinyl]-benzeneacetic acid
Application:	CaSR agonist
CAS	870964-67-3
MW:	374.5 D

From 85.00€ *

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