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MK-0893
MK-0893

Item number: Cay28923-1

A GCGR antagonist (IC50 = 15.7 nM), selective for GCGR over GIPR, GLP-1R, PAC1, VPAC1, and VPAC2 (IC50s = 1,020, >10,000, 9,200, 11,580, and 12,800 nM, respectively), reduces glucagon-induced increases in blood glucose levels in rhesus monkeys at 1 and 3 mg/kg. SMILES:...
Keywords: N-[4-[(1S)-1-[3-(3,5-dichlorophenyl)-5-(6-methoxy-2-naphthalenyl)-1H-pyrazol-1-yl]ethyl]benzoyl]-beta-alanine
Application: GCGR antagonist
CAS 870823-12-4
MW: 588.48 D
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