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Item number: Cay43589-10

AC-261066 is a retinoic acid receptor beta2 (RARbeta2) agonist. It selectively induces RARbeta2 activity over RARbeta1 activity in functional assays using mammalian cells (EC50s = 10 and >10,000 nM, respectively). AC-261066 is also selective for RARbeta over RARalpha and RARgamma (EC50s = 12, 70, and 33 nM,...

Keywords:	4-[4-(2-butoxyethoxy)-5-methyl-2-thiazolyl]-2-fluoro-benzoic acid
Application:	RARbeta2 agonist
CAS	870773-76-5
MW:	353.41 D

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AC-261066

Item number: TGM-T14089-100mg

Description: AC-261066 is an orally available and isoform-selective agonist of RARbeta2 with a pEC50 of 8.0. Target: Retinoid Receptor. Smiles: CCCCOCCOc1nc(sc1C)-c1ccc(C(O)=O)c(F)c1. References: Lund BW, et al. Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. J...

Keywords:	AC 261066
CAS	870773-76-5
MW:	353.41 D

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