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IMB-808
IMB-808

Item number: Cay42448-10

An agonist of LXRalpha and LXRbeta, induces transactivation of LXRalpha and LXRbeta in reporter assays using HEK293T cells (EC50s = 0.15 and 0.53 µM, respectively), increases protein levels of ABCG1 and ABCA1 in RAW 264.7 and THP-1 cells at 1 or 10 µM, induces cholesterol efflux and reduces oxidized LDL-induced...
Keywords: 2,3-dihydro-N-methyl-N-[2-oxo-2-[(2,3,4-trifluorophenyl)amino]ethyl]-1,4-benzodioxin-6-carboxamide
Application: LXRalpha / LXRbeta agonist
CAS 870768-70-0
MW: 380.32 D
From 107.00€ *
Review
IMB-808
IMB-808

Item number: TGM-T25528-2mg

Description: IMB-808 is an LXRalpha/beta dual agonist that promotes ABCA1 expression and cholesterol efflux without inducing lipidogenesis in HepG2 cells. IMB-808 can be used in atherosclerosis research. Target: Antibacterial, Liver X Receptor. Smiles: O=C(C1=CC=C2OCCOC2=C1)N(C)CC(=O)NC3=CC=C(F)C(F)=C3F
Keywords: IMB808
CAS 870768-70-0
MW: 380.32 D
From 43.00€ *
Review