3 products were found matching "870483-87-7"!

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Item number: Cay15411-25

cFMS kinase is the cellular homolog of the v-FMS oncogene product of the Susan McDonough strain of the feline sarcoma virus. It can autophosphorlyate colony-stimulating factor (CSF-1), which promotes the survival, proliferation, and differentiation of mononuclear phagocytes. GW 2580 selectively inhibits cFMS kinase...

Keywords:	5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Application:	CSF1R kinase inhibitor
CAS	870483-87-7
MW:	366.4 D

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GW2580, Free Base...

Item number: G9951-25.100

GW2580 is a small-molecule inhibitor of cFMS kinase, at 60nM it inhibited human cFMS kinase completely in vitro and was inactive against 26 other kinases. GW2580 inhibited lipopolysaccharide (LPS)-induced TNF production in mice, but not LPS-induced TNF production in freshly isolated human monocytes and mouse...

CAS	870483-87-7
MW:	366.41

294.00€ *

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GW2580, Free Base (cFMS Receptor Tyrosine Kinase...

Item number: LC-G-5903_10g

Soluble in DMSO at 40 mg/mL, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 20-100 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility

Keywords:	5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Application:	CSF1R kinase inhibitor
CAS	870483-87-7
MW:	366,41 D

From 137.00€ *

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Review

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