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Item number: Cay25983-1

Acalisib is an inhibitor of the class I phosphatidylinositol 3-kinase (PI3K) catalytic subunit p110delta (IC50 = 12.7 nM). It is selective for p110delta over the class I PI3K subunits p110alpha, p110beta, p110gamma, the class II PI3K CIIbeta, and the class III PI3K hVPS34 (IC50s = 5.4, 3.3, 1.4, 10, and 12.6 µM,...

Keywords:	GS-9820, 6-fluoro-3-phenyl-2-[(1S)-1-(9H-purin-6-ylamino)ethyl]-4(3H)-quinazolinone
Application:	PI3K catalytic subunit p110delta inhibitor
CAS	870281-34-8
MW:	401.4 D

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