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Item number: Cay28452-10

Tozadenant is an adenosine A2A receptor antagonist (Kis = 11.5 and 6 nM for the human and rhesus monkey receptors, respectively). It increases the distance traveled and reduces contralateral asymmetry in the open field test in a rat model of Parkinson's disease induced by 6-OHDA (Cay-25330) when administered at a...

Keywords:	4-hydroxy-N-[4-methoxy-7-(4-morpholinyl)-2-benzothiazolyl]-4-methyl-1-piperidinecarboxamide
Application:	Adenosine A2B receptor antagonist
CAS	870070-55-6
MW:	406.5 D

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Tozadenant

Item number: TGM-T7320-100mg

Description: Tozadenant (SYN115) is an adenosine A2A receptor antagonist(Ki of 11.5 nM and 6 nM on human and rhesus",respectively). Target: Adenosine Receptor. Smiles: COc1ccc(N2CCOCC2)c2sc(NC(=O)N3CCC(C)(O)CC3)nc12. References: Hauser R A , Olanow C W , Kieburtz K D ," et al. Tozadenant (SYN115) in patients with...

Keywords:	SYN115
Application:	Targets adenosine receptor A2a (ADORA2A, ADOR)
CAS	870070-55-6
MW:	406.5 D

From 36.00€ *

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