3 products were found matching "869357-68-6"!

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Item number: Cay11588-1

AZD 8330 is a selective allosteric inhibitor of MEK1/2 (IC50 = 7 nM). It blocks phosphorylation of ERK1/2 and inhibits proliferation of certain cancer cells. AZD 8330 is orally bioavailable, inhibits ERK phosphorylation in vivo, and reduces tumor growth in a Calu-6 nude rat xenograft model.Formal Name:...

Keywords:	ARRY-424704, 2-[(2-fluoro-4-iodophenyl)amino]-1,6-dihydro-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-3-pyridinecarboxamide
Application:	MEK inhibitor
CAS	869357-68-6
MW:	461.2 D

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AZD-8330

Item number: SYN-1195-M001

Soluble in DMSO or ethanol. AZD8330 is a novel, selective, non-ATP competitive MEK 1/2 inhibitor with an IC(50) of 7nM. Target: MEK1 - MEK2 , Kinase Group: STE , Substrate: Serine-Threonine

Keywords:	AZD8330
Application:	MEK1 / MEK2 inhibitor
CAS	869357-68-6
MW:	461,2 D

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AZD8330

Item number: LKT-A9715.1

AZD8330 is an inhibitor of MEK1/2 that exhibits anticancer chemotherapeutic activity. AZD8330 is currently in clinical trials for the treatment of advanced stage cancers.

Keywords:	ARRY-704, ARRY-424704
Application:	MEK1/2 inhibitor
CAS	869357-68-6
MW:	461.23 D

From 205.00€ *

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