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SB 203580 hydrochloride

Item number: TGM-T21675-10mg

Description: Adezmapimod (SB 203580) hydrochloride is a selective ATP-competitive inhibitor of p38 MAPK, with IC50 values of 50 nM for SAPK2a/p38 and 500 nM for SAPK2b/p38beta2. This compound also inhibits LCK, GSK3beta, and PKBalpha with IC50 values 100-500 times higher than those for SAPK2a/p38. Additionally,...

CAS	869185-85-3
MW:	413.9 D

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SB 203580 (hydrochloride)

Item number: Cay13344-5

Mitogen-activated protein kinases (MAPKs) mediate signal transduction from cell surface receptors to the nucleus and are classified into various subtypes. p38 MAPK is activated by environmental stresses and inflammatory cytokines and is critical for normal immune and inflammatory responses as it regulates the...

Keywords:	PB 203580, RWJ 64809, 4-[4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl]-pyridine, monohydrochloride
Application:	p38 MAPK inhibitor
CAS	869185-85-3
MW:	413.9 D

From 152.00€ *

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