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RO-0335
Item number: TGM-T9223-100mg
Description: RO-0335 is a potent diphenylether nonnucleoside reverse transcriptase inhibitor. RO-0335 inhibits Wt HIV-1 (IC50 = 1.1 nM) and retained activity (IC50< 100 nM) against 92% of a large number of NNRTI-resistant clinical isolates. Target: Reverse Transcriptase. Smiles:...
| Application: | Elsulfavirine active metabolite, non-nucleoside reverse transcriptase inhibitor (NNRTI) |
| CAS | 867365-76-2 |
| MW: | 573.22 D |
From 48.00€
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Ro 0335
Item number: Cay36124-10
Ro 0335 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and an active metabolite of the antiviral prodrug elsulfavirine. It inhibits HIV-1 reverse transcriptase in a cell-free assay and the replication of HIV-1 in MT-4 cells (IC50s = 8.1 and 1.1 nM, respectively). Ro 0335 also selectively inhibits human...
| Keywords: | VM 1500A, N-[4-(aminosulfonyl)-2-chlorophenyl]-4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluoro-benzeneacetamide |
| Application: | Elsulfavirine active metabolite, non-nucleoside reverse transcriptase inhibitor (NNRTI) |
| CAS | 867365-76-2 |
| MW: | 573.2 D |
From 122.00€
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