3 products were found matching "867160-71-2"!
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Linsitinib
Item number: Cay17708-1
The binding of insulin-like growth factor 1 (IGF-1) to the IGF-1 receptor (IGF-1R) promotes cell growth while inhibiting apoptotic pathways. Overexpression of IGF-1R is found in certain solid tumors and hematologic neoplasias. However, insulin receptor (InsR) signaling can compensate for IGF-1R inhibition....
| Keywords: | OSI-906, cis-3-[8-amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol |
| Application: | IGF-1R & InsR kinase inhibitor |
| CAS | 867160-71-2 |
| MW: | 421.5 D |
From 62.00€
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OSI-906
Item number: LKT-O7333.5
IGF-1R and InsR inhibitor.
| Keywords: | OSI906, Linsitinib |
| Application: | Insulin-like growth factor 1 receptor |
| CAS | 867160-71-2 |
| MW: | 421.49 D |
From 136.00€
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Linsitinib
Item number: TGM-T6017-100mg
Description: OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of...
| Keywords: | OSI-906 |
| Application: | Targets insulin-like growth factor 1 receptor [EC:2.7.10.1] (IGF1R, CD221) |
| CAS | 867160-71-2 |
| MW: | 421.49 D |
From 32.00€
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