Description: Preq1-Dihydrochloride (pre-queuosine1 Dihydrochloride) is an intermediate of the queuosine pathway, it binds with high affinity to the aptamer of PreQ1 riboswitch, which attenuates protein expression. Target: Others. Smiles: Cl.Cl.NCc1c[nH]c2nc(N)[nH]c(=O)c12. References: Vlack E V , Topp S , Seeliger J...

preQ1 is a precursor in the biosynthesis of queuosine, a bacterial nucleoside incorporated into tRNA by tRNA transglycosylase. preQ1 binds to an aptamer domain on tRNA that acts as a riboswitch to repress gene expression.Formal Name: 2-amino-5-(aminomethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one,...