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Trelagliptin
Item number: Cay18504-1
Trelagliptin is an inhibitor of dipeptidyl peptidase 4 (DPP-4, IC50 = 4 nM). It is greater than 10,000-fold selective for DPP-4 over isopeptidases. Trelagliptin (7 mg/kg) inhibits plasma DPP-4 activity and reduces postprandial plasma insulin levels in Zucker fa/fa rats. Formulations containing trelagliptin have been...
| Keywords: | SYR-472, 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-4-fluoro-benzonitrile |
| Application: | DPP4 inhibitor |
| CAS | 865759-25-7 |
| MW: | 357.4 D |
From 93.00€
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Trelagliptin
Item number: TGM-T6237-100mg
Description: Trelagliptin (SYR-472) is a highly specific, long-acting DPP-4 inhibitor. Target: DPP-4, Proteasome. Smiles: Cn1c(=O)cc(N2CCC[C@@H](N)C2)n(Cc2cc(F)ccc2C#N)c1=O. References: Inagaki N, et al. Lancet Diabetes Endocrinol. 2014, 2(2), 125-132.
| Keywords: | SYR-472 |
| Application: | Targets dipeptidyl-peptidase 4 [EC:3.4.14.5] (DPP4, CD26) |
| CAS | 865759-25-7 |
| MW: | 357.38 D |
From 39.00€
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