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Islatravir
Item number: TGM-T16098-100mg
Description: Islatravir (MK-8591) is an effective anti-HIV-1 agent. It acts as a nucleoside reverse transcriptase inhibitor (EC50s: 0.068 nM, 3.1 nM, and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively). Target: Reverse Transcriptase, HIV Protease. Smiles:...
| Keywords: | MK-8591 |
| Application: | Targets HIV-1 reverse transcriptase / ribonuclease H [EC:2.7.7.49 2.7.7.7 3.1.26.13] (RT) |
| CAS | 865363-93-5 |
| MW: | 293.25 D |
From 72.00€
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EFdA
Item number: Cay33873-1
EFdA is a nucleoside reverse transcriptase inhibitor (NRTI). It inhibits HIV-1 reverse transcriptase via multiple mechanisms. EFdA inhibits replication of the HIV-1 strain HIV-1 IIIb, the laboratory isolate HIV NL4-3, and the clinical isolate HIV-2 EHO in MT-4 cells (EC50s = 73, 50, and 98 pM, respectively). It is...
| Keywords: | 4'Ed2FA, 4'-ethynyl-2-fluoro-2'-Deoxyadenosine, EFDA, MK-8591, 2'-deoxy-4'-C-ethynyl-2-fluoro-adenosine |
| Application: | Nucleoside reverse transcriptase inhibitor |
| CAS | 865363-93-5 |
| MW: | 293.3 D |
From 166.00€
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