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Item number: Cay37756-1

NEDD8 inhibitor M22 is an inhibitor of NEDD8-activating enzyme (NAE). It inhibits NEDDylation of ubiquitin-conjugating enzyme 12 (UBC12) in a cell-free assay using recombinant human NAE in a concentration-dependent manner. NEDD8 inhibitor M22 selectively inhibits NEDDylation over SUMOylation and ubiquitination in...

Keywords:	NAE-IN-M22, NEDD8-activating Enzyme Inhibitor M22, N-[2-(2,4-dichlorophenyl)ethyl]-1-(phenylmethyl)-4-piperidinamine
Application:	NEDD8-activating enzyme inhibitor
CAS	864420-54-2
MW:	363.3 D

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