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BTB-1
BTB-1

Item number: Cay27219-250

BTB-1 is a reversible inhibitor of the kinesin-8 family motor protein Kif18A (IC50 = 1.69 µM). It is selective for Kif18A over a panel of seven kinesins at 100 µM. BTB-1 (100 µM) inhibits Kif18A-dependent microtubule motility in a microtubule gliding assay. It induces mitotic accumulation of HeLa cells in a...
Keywords: NSC 156750, NSC 658180, 4-chloro-2-nitro-1-(phenylsulfonyl)-benzene
Application: Kif18A inhibitor
CAS 86030-08-2
MW: 297.7 D
From 60.00€ *
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BTB-1
BTB-1

Item number: TGM-T4029-100mg

Description: BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A. Target: Microtubule Associated. Smiles: [O-][N+](=O)C1=C(C=CC(Cl)=C1)S(=O)(=O)C1=CC=CC=C1. References: Catarinella M., et al. BTB-1: a small molecule inhibitor of the mitotic motor protein Kif18A. Angew Chem Int...
Keywords: NSC156750, BTB 1
Application: Kif18A inhibitor
CAS 86030-08-2
MW: 297.71 D
From 30.00€ *
Review