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(R)-(-)-Rolipram
Item number: TGM-T13448-10mg
Description: (R)-(-)-Rolipram ((-)-Rolipram) is an R-enantiomer of Rolipram which is a PDE4 inhibitor. Target: DNA-PK, Others. Smiles: COc1ccc(cc1OC1CCCC1)[C@@H]1CNC(=O)C1. References: Guo C, et al. Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. Immunity. 2016 Oct...
| Keywords: | (R)-Rolipram, (-)-Rolipram |
| Application: | PDE4 inhibitor |
| CAS | 85416-75-7 |
| MW: | 275.34 D |
From 40.00€
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(-)-Rolipram
Item number: Cay31111-1
(-)-Rolipram is a phosphodiesterase 4 (PDE4) inhibitor (IC50 = 0.22 µM for the guinea pig eosinophil enzyme) and an enantiomer of (±)-rolipram (Cay-10011132). It enhances isoprenaline-induced cAMP accumulation in isolated guinea pig eosinophils (EC50 = 0.19 µM). (-)-Rolipram (1-1,000 µM) inhibits TNF and INF-gamma...
| Keywords: | (R)-(-)-Rolipram, (R)-Rolipram, (4R)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone |
| Application: | PDE4 inhibitor |
| CAS | 85416-75-7 |
| MW: | 275.3 D |
From 52.00€
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