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Item number: Cay19903-10

Wnt Agonist I is a cell-permeable activator of Wnt signaling that does not inhibit GSK3beta (IC50 > 60 µM). It induces nuclear accumulation of beta-catenin, increasing transcriptional activity driven by TCF (EC50 = 700 nM) and altering embryonic development. Wnt Agonist I is effective in vivo, decreasing tissue...

Keywords:	BML-284, N4-(1,3-benzodioxol-5-ylmethyl)-6-(3-methoxyphenyl)-2,4-pyrimidinediamine
Application:	Cell-permeable Wnt signaling activator
CAS	853220-52-7
MW:	350.4 D

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BML-284

Item number: TGM-T3144-5mg

Description: BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator. Target: Wnt/beta-catenin. Smiles: COc1cccc(c1)-c1cc(NCc2ccc3OCOc3c2)nc(N)n1. References: Angew Chem Int Ed Engl. 2005, 44(13), 1987-1990.

Keywords:	Wnt agonist 1
Application:	Cell-permeable Wnt signaling activator
CAS	853220-52-7
MW:	350.37 D

From 52.00€ *

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