The following products have been found matching your search "852808-04-9": 3

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ABT-737
ABT-737

Item number: Cay11501-25

The family of Bcl-2 proteins plays pivotal roles in either promoting or preventing apoptosis. Bcl-2 family members contain one or more of four characteristic Bcl-2 homology (BH) domains, which are crucial for function. For example, anti-apoptotic Bcl-2 family proteins prevent death signaling by heterodimerizing with...
Keywords: 4-[4-[(4'-chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]am...
Application: Potent, cell-permeable BH3 domain mimetic
CAS 852808-04-9
MW: 813.4 D
From 82.00€ *
Review
ABT-737
ABT-737

Item number: SYN-1001-M001

Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. ABT-737 is a small-molecule inhibitor of the anti-apoptotic proteins Bcl-2, Bcl-X(L) and Bcl-w, with an affinity two to three orders of magnitude more potent than previously reported compounds. Mechanistic studies reveal that ABT-737 does not directly initiate...
Keywords: ABT737
Application: Bcl-2 / Bcl-X(L) / Bcl-w inhibitor
CAS 852808-04-9
MW: 813,4 D
From 79.00€ *
Review
ABT-737
ABT-737

Item number: LKT-A0778.1

BH3 mimetic, Bcl-2, Bxl-xl, Bcl-w inhibitor
Keywords: ABT737
Application: BH3 mimetic, Bcl-2, Bxl-xl, Bcl-w inhibitor
CAS 852808-04-9
MW: 813.43 D
From 107.00€ *
Review