4 products were found matching "852808-04-9"!
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ABT-737
Item number: TGM-T2099-100mg
Description: ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w (EC50s: 78.7/30.3/197.8 nM). Target: Autophagy, Mitophagy, BCL. Smiles: CN(C)CCC(CSc1ccccc1)Nc1ccc(cc1[N+]([O-])=O)S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(Cc2ccccc2-c2ccc(Cl)cc2)CC1. References: Konopleva M, et al. Mechanisms of apoptosis...
| CAS | 852808-04-9 |
| MW: | 813.43 D |
From 63.00€
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ABT-737
Item number: Cay11501-25
The family of Bcl-2 proteins plays pivotal roles in either promoting or preventing apoptosis. Bcl-2 family members contain one or more of four characteristic Bcl-2 homology (BH) domains, which are crucial for function. For example, anti-apoptotic Bcl-2 family proteins prevent death signaling by heterodimerizing with...
| Keywords: | 4-[4-[(4'-chloro[1,1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]am... |
| Application: | Potent, cell-permeable BH3 domain mimetic |
| CAS | 852808-04-9 |
| MW: | 813.4 D |
From 39.00€
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ABT-737
Item number: SYN-1001-M005
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. ABT-737 is a small-molecule inhibitor of the anti-apoptotic proteins Bcl-2, Bcl-X(L) and Bcl-w, with an affinity two to three orders of magnitude more potent than previously reported compounds. Mechanistic studies reveal that ABT-737 does not directly initiate...
| Keywords: | ABT737 |
| Application: | Bcl-2 / Bcl-X(L) / Bcl-w inhibitor |
| CAS | 852808-04-9 |
| MW: | 813,4 D |
From 92.00€
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ABT-737
Item number: LKT-A0778.1
BH3 mimetic, Bcl-2, Bxl-xl, Bcl-w inhibitor
| Keywords: | ABT737 |
| Application: | BH3 mimetic, Bcl-2, Bxl-xl, Bcl-w inhibitor |
| CAS | 852808-04-9 |
| MW: | 813.43 D |
From 131.00€
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