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Amuvatinib
Item number: SYN-1056-M001
Soluble in DMSO or ethanol. Amuvatinib is a potent, novel and orally active multi-targeted tyrosine kinase inhibitor, which inhibits a number of validated tumor targets including c-kit, PDGFRalpha and flt3, with IC(50) values of 10nM, 40nM and 81nM respectively. Target: PDGFR , Kinase Group: RTK , Substrate: Tyrosine
| Keywords: | MP-470 |
| Application: | c-KIT / PDGFR inhibitor |
| CAS | 850879-09-3 |
| MW: | 447,5 D |
From 154.00€
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Amuvatinib
Item number: Cay21461-1
Amuvatinib is a multi-targeted inhibitor of receptor tyrosine kinases that inhibits c-Kit, platelet-derived growth factor receptor alpha (PDGFRalpha), and c-Met (IC50s = 10, 40, and 81 nM, respectively). It inhibits growth and induces apoptosis in prostate cancer cell lines, with additive effects achieved when...
| Keywords: | HPK56, MP470, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro[3,2-d]pyrimidin-4-yl-1-piperazinecarbothioamide |
| Application: | KIT receptor tyrosine kinase inhibitor |
| CAS | 850879-09-3 |
| MW: | 447.5 D |
From 150.00€
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Amuvatinib
Item number: TGM-T2516-100mg
Description: Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity. Target: c-Kit, Apoptosis, c-RET, c-Met/HGFR, FLT, DNA/RNA Synthesis, PDGFR. Smiles: C(NCC=1C=C2C(=CC1)OCO2)(=S)N3CCN(C4=C5C(C=6C(O5)=CC=CC6)=NC=N4)CC3. References: Hurley LH, et al. World...
| Keywords: | MP470, HPK 56 |
| CAS | 850879-09-3 |
| MW: | 447.51 D |
From 45.00€
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