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Danoprevir
Item number: Cay24185-1
Danoprevir is an orally bioavailable inhibitor of hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A, IC50 = 1 nM), a serine protease essential for HCV replication. It is selective for NS3/4A over a panel of 53 proteases at a concentration of 10 µM. Danoprevir inhibits replication of the HCV genotypes 1a,...
| Keywords: | ITMN-191, R-7227, 4-fluoro-1,3-dihydro-2H-isoindole-2-carboxylic acid,... |
| Application: | Hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A) inhibitor |
| CAS | 850876-88-9 |
| MW: | 731.8 D |
From 93.00€
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Danoprevir
Item number: LKT-D017538.1
Danoprevir is a NS3/4A protease inhibitor. The hepatitis C viral replication is thought to relate to the HCV NS3/4A protease, the inhibition of which is a target of drug development.
| Keywords: | lopentadecin-2-yl 4-fluoroisoindoline-2-carboxylate, ITMN-191, RO5190591, RG 7227,... |
| Application: | Antiviral (hepatitis C) |
| CAS | 850876-88-9 |
| MW: | 731.83 D |
From 116.00€
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Danoprevir
Item number: TGM-T6025-100mg
Description: Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV). Target: HCV Protease, SARS-CoV. Smiles: CC(C)(C)OC(=O)N[C@H]1CCCCC\C=C/[C@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C1=O)OC(=O)N1Cc2cccc(F)c2C1)C(=O)NS(=O)(=O)C1CC1. References: Seiwert SD, et...
| Keywords: | RO5190591, RG7227, ITMN-191, R7227 |
| Application: | Antiviral, Protease inhibitor |
| CAS | 850876-88-9 |
| MW: | 731.83 D |
From 54.00€
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