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GSK269962A
Item number: TGM-T3518-100mg
Description: GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively. Target: ROCK, S6 Kinase. Smiles: CCn1c(nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc12)-c1nonc1N. References: Doe C, et al. J Pharmacol Exp...
| Keywords: | GSK269962B, GSK269962A HCl, GSK 269962 |
| Application: | Selective ROCK inhibitor |
| CAS | 850664-21-0 |
| MW: | 570.6 D |
From 37.00€
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GSK269962
Item number: Cay19180-1
Two Rho-associated kinases (ROCKS), ROCK1 and ROCK2, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. GSK269962 is a selective ROCK...
| Keywords: | GSK269962A, GSK269962B,... |
| Application: | Selective ROCK inhibitor |
| CAS | 850664-21-0 |
| MW: | 570.6 D |
From 52.00€
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