- Search results for 850140-73-7
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3 products were found matching "850140-73-7"!
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Item number: Cay21567-1
Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein. Afatinib (20 mg/kg) reduces...
| Keywords: | Afatinib dimaleate, BIBW 2992, BIBW 2992MA2,... |
| Application: | EGFR / ERBB2 / ERBB4 inhibitor |
| CAS | 850140-73-7 |
| MW: | 718.1 D |
From 146.00€
*
Item number: TGM-T1773-10mg
Description: Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB, EGFR) family, with antineoplastic activity. Target: Autophagy, EGFR, HER. Smiles:...
| Keywords: | Afatinib, BIBW2992, BIBW 2992MA2, Afatinib (BIBW2992) Dimaleate |
| Application: | EGFR / ERBB2 / ERBB4 inhibitor |
| CAS | 850140-73-7 |
| MW: | 718.08 D |
From 32.00€
*
Item number: Cay21567-100
Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein. Afatinib (20 mg/kg) reduces...
| Keywords: | Afatinib dimaleate, BIBW 2992, BIBW 2992MA2,... |
| Application: | EGFR / ERBB2 / ERBB4 inhibitor |
| CAS | 850140-73-7 |
| MW: | 718.1 D |
73.00€
*
