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Afatinib (maleate)
Afatinib (maleate)

Item number: Cay21567-1

Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein. Afatinib (20 mg/kg) reduces...
Keywords: Afatinib dimaleate, BIBW 2992, BIBW 2992MA2,...
Application: EGFR / ERBB2 / ERBB4 inhibitor
CAS 850140-73-7
MW: 718.1 D
From 146.00€ *
Review
Afatinib Dimaleate
Afatinib Dimaleate

Item number: TGM-T1773-10mg

Description: Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB, EGFR) family, with antineoplastic activity. Target: Autophagy, EGFR, HER. Smiles:...
Keywords: Afatinib, BIBW2992, BIBW 2992MA2, Afatinib (BIBW2992) Dimaleate
Application: EGFR / ERBB2 / ERBB4 inhibitor
CAS 850140-73-7
MW: 718.08 D
From 32.00€ *
Review
Afatinib (maleate)
Afatinib (maleate)

Item number: Cay21567-100

Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein. Afatinib (20 mg/kg) reduces...
Keywords: Afatinib dimaleate, BIBW 2992, BIBW 2992MA2,...
Application: EGFR / ERBB2 / ERBB4 inhibitor
CAS 850140-73-7
MW: 718.1 D
73.00€ *
Review