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1G244
Item number: Cay18306-10
1G244 is an inhibitor of dipeptidyl peptidase 8 (DPP-8) and DPP-9 (IC50s = 14 and 53 nM, respectively). It is selective for DPP-8 and DPP-9 over DPP-4, DPP-2, and fibroblast activation protein (FAP, IC50s = >100 µM for all). 1G244 (20 µM) inhibits the differentiation of 3T3-L1 cells into adipocytes. It induces...
| Keywords: | PTX1210, 2S-amino-4-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-1-(1,3-dihydro-2H-isoindol-2-yl)-1,4-butanedione |
| Application: | DPP8/DPP9 inhibitor |
| CAS | 847928-32-9 |
| MW: | 504.6 D |
From 112.00€
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1G244
Item number: TGM-T14005-100mg
Description: 1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties. 1G244 had the IC50 values of 14 and 53 nM against DPP8 and DPP9, and The Ki values for 1G244 were 0.9 and 4.2 nM for DPP8 and DPP9. Target: Proteasome. Smiles:...
| CAS | 847928-32-9 |
| MW: | 504.57 D |
From 32.00€
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