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CJ-42794
CJ-42794

Item number: TGM-T14975-10mg

Description: CJ-42794 (CJ-042794) is a selective antagonist of the prostaglandin E receptor subtype 4 (EP4), inhibiting [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5. It exhibits a binding affinity that is at least 200-fold more selective for the human EP4 receptor than for other human EP...
Keywords: CJ-042794
Application: EP4 receptor agonist
CAS 847728-01-2
MW: 413.83 D
From 33.00€ *
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CJ-42794
CJ-42794

Item number: Cay10010428-10

Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CJ-42794 is a selective antagonist of EP4 (Ki = 3.16 nM) that less...
Keywords: RQ-00015986, 4-[(1S)-1-[[5-chloro-2-(4-fluorophenoxy)benzoyl]amino]ethyl]-benzoic acid
Application: EP4 receptor agonist
CAS 847728-01-2
MW: 413.8 D
From 73.00€ *
Review